Figure 5
From: PK/PD investigation of antiviral host matriptase/TMPRSS2 inhibitors in cell models
Time course of depletion of the protease inhibitors in primary human hepatocytes. Relative percentage values of the unchanged amount of parent compounds were calculated by dividing the concentrations of the inhibitor measured at the given time point by the mean starting amount of the inhibitors in the treatment solution (mean ± S.E.M.); n = 3/group. Asterisks indicate significant differences compared to starting values of the indicated inhibitors at 120 min in parentheses (**p < 0.01, ***p < 0.001).
