Table 2 Performance of the four linear SVM classifiers on the test set when the features are defined using a cut-off of 0.1 on the log2 copy ratio. The features (Segments, Size and Chromosomes), considered as covariates in the four linear SVM classifiers, were defined using a cut-off of 0.1 on the log2 copy ratio. The performance of the best model for each classifier was evaluated on the test set (n = 60) in terms of accuracy, specificity, sensitivity, balanced accuracy and area under the ROC curve (AUROC). TP: true positives; TN: true negatives; FP: false positives; FN: false negatives.
Cut off = 0.1 | TP | TN | FP | FN | Overall accuracy | Overall specificity | Overall sensitivity | Balanced accuracy | AUROC |
|---|---|---|---|---|---|---|---|---|---|
3f | 10 | 49 | 0 | 1 | 0.9833 | 1.0000 | 0.9091 | 0.9545 | 1.0000 |
2f Segments—Size | 10 | 49 | 0 | 1 | 0.9833 | 1.0000 | 0.9091 | 0.9545 | 1.0000 |
2f Size—Chromosomes | 10 | 49 | 0 | 1 | 0.9833 | 1.0000 | 0.9091 | 0.9545 | 1.0000 |
2f Segments—Chromosomes | 10 | 48 | 1 | 1 | 0.9667 | 0.9796 | 0.9091 | 0.9443 | 0.9981 |