Figure 1
From: Lipidomic study of kidney in a mouse model with urine flow obstruction
Tubulointerstitial lesion (TIL) in unilateral ureteral obstruction (UUO) mouse models. (a) Histopathological features of TILs in sham control and UUO mice. The tubular injury in the UUO kidney is characterized by the dilatation of tubules with the urinary cast (arrowhead). Mild and severe TIL were observed in UUO kidney at 4 and 7 days respectively. Periodic acid Schiff-hematoxylin (PAS-H) staining. (b–d) Analysis of B220+ B-cell, CD3+ T-cells, and Iba-1+ macrophage (arrows) infiltration in sham control and TILs of UUO mice. Immunohistochemistry. All bars = 100 μm.
