Table 1 Gene expression model and protein expression model for predicting S2, S3 and S4 molecular subtypes.
GBM molecular subtypes | Gene Expression (TCGA) | Accuracy (%) | Protein Expression (RPPA) | Accuracy (%) |
|---|---|---|---|---|
S2 | C5orf38 | 96.7 | CJUN_pS73 | 84.6 |
NPPA | CMYC | |||
NKAIN1 | CRAF_pS338 | |||
NHLH1 | CYCLINB1 | |||
IRX2 | DVL3 | |||
PCDH15 | EGFR_pY1173 | |||
KLRC3 | NOTCH1 | |||
FBN3 | P38_pT180Y182 | |||
GFRA1 | PKCDELTA_pS664 | |||
RASL11B | SRC | |||
MEX3B | STATHMIN | |||
RCOR2 | VEGFR2 | |||
MDGA2 | BRCA2 | |||
| Â | MYH11 | |||
| Â | TFRC | |||
| Â | ANNEXIN1 | |||
| Â | PD-L1 | |||
S3 | F13A1 | 86.7 | GSK3ALPHABETA | 38.5 |
CYP1B1 | PAI1 | |||
COL6A3 | Â | |||
IGFBP6 | Â | |||
MRC1 | Â | |||
IL6 | Â | |||
CHRNA9 | Â | |||
CAMP | Â | |||
LOX | Â | |||
SCNN1B | Â | |||
PODNL1 | Â | |||
NAMPT | Â | |||
MOXD1 | Â | |||
PLA2G5 | Â | |||
LGALS3 | Â | |||
C15orf48 | Â | |||
LY96 | Â | |||
S4 | DMRTA2 | 93.3 | X4EBP1_pT37T46 | 84.6 |
GAS1 | X53BP1 | |||
ACSBG1 | BAX | |||
CDH4 | ECADHERIN | |||
EYA2 | EEF2K | |||
AFAP1L1 | HER2_pY1248 | |||
ADGRE5 | NFKBP65_pS536 | |||
LKAAEAR1 | NF2 | |||
ERFE | S6_pS240S244 | |||
ETV4 | SMAD1 | |||
DENND2A | SRC | |||
CREB5 | STATHMIN | |||
ACSL3 | GAPDH | |||
CCND2 | HEREGULIN | |||
| Â | GATA6 | |||
| Â | BRD4 | |||
| Â | DUSP4 | |||
| Â | P16INK4A |
