Figure 3 | Scientific Reports

Figure 3

From: Quality by design approach of apocynin loaded clove oil based nanostructured lipid carrier as a prophylactic regimen in hemorrhagic cystitis in vitro and in vivo comprehensive study

Figure 3

Representative microphotographs of (A) Rat’s bladder sections, H&E stained, from all experimental groups. Black arrows point to mucosal atrophy and ulceration. Yellow arrows point to capillary congestion. Green arrows point to stromal reactions. Blue arrowheads point to interstitial edema and hemorrhage. Low magnification (X: 100, bar: 100 µm). (B) Immune-stained bladder sections against NF-κB in all experimental groups. Black arrows point to negative IHC staining. White arrows point to positive or brown cytoplasmic expression, high magnification (X: 200, bar: 50 µm). (C) Immune-stained bladder sections against COX-2 in all experimental groups. Black arrows point to negative IHC staining. White arrows point to positive or brown cytoplasmic expression, high magnification (X: 200, bar: 50 µm).

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