Table 2 Differential expression analysis of the studied miRNAs between breast cancer patients and controls and their implications for tumor suppression and oncogenic activity.

From: Evaluation of tumorigenesis-related miRNAs in breast cancer in Egyptian women: a retrospective, exploratory analysis

miRNA

Function

Control N = 20

BC Patients N = 75

P value

miR-200a-3p

Tumor Suppressor 19

0.19(0.1–0.2)

0.003(0.002–0.003)

0.00009

miR-205-5p

Tumor Suppressor 20

1.04(0.6–1.6)

0.5(0.2–1.1)

0.015

miR-124-3p

Tumor Suppressors21

1.1 (0.6–1.7)

0.25(0.12–0.57)

0.012

miR-15a-5p

Tumor Suppressors 20

0.9(0.3–1.3)

1.3(0.3–1.9)

0.2

miR-155-5p

Oncogenic 22

1.07(0.4–2.1)

0.92(0.22–3.32)

0.72

  1. Data are expressed as median and interquartile range (IQR).
  2. Bold indicated significant P value.
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