Table 1 Demographics and clinicopathologic characteristics of non-secondary primary malignancies and the secondary primary malignancies group in the GC patients.
From: Analyzing risk factors for second malignancies in early gastric carcinoma from the SEER database
Variables | Total (n = 3289) | NOSM (n = 3134) | OSM (n = 155) | P |
|---|---|---|---|---|
Age.cat, n (%) | 0.159 | |||
18–65 | 1017 (30.9) | 969 (30.9) | 48 (31) | |
66–75 | 944 (28.7) | 890 (28.4) | 54 (34.8) | |
76–100 | 1328 (40.4) | 1275 (40.7) | 53 (34.2) | |
Sex, n (%) | 0.173 | |||
Female | 1220 (37.1) | 1171 (37.4) | 49 (31.6) | |
Male | 2069 (62.9) | 1963 (62.6) | 106 (68.4) | |
Race, n (%) | 0.973 | |||
White | 2357 (71.7) | 2246 (71.7) | 111 (71.6) | |
Black | 397 (12.1) | 379 (12.1) | 18 (11.6) | |
Others | 535 (16.3) | 509 (16.2) | 26 (16.8) | |
Marital, n (%) | 0.086 | |||
Married | 1795 (54.6) | 1699 (54.2) | 96 (61.9) | |
Divorced/Separated | 293 (8.9) | 285 (9.1) | 8 (5.2) | |
Single/UnMarried | 385 (11.7) | 364 (11.6) | 21 (13.5) | |
Widowed/Others | 816 (24.8) | 786 (25.1) | 30 (19.4) | |
Diagnosis, n (%) | 0.005 | |||
2010–2012 | 1644 (50) | 1549 (49.4) | 95 (61.3) | |
2013–2015 | 1645 (50) | 1585 (50.6) | 60 (38.7) | |
AJCCa, n (%) | 0.804 | |||
IA | 2896 (88.1) | 2761 (88.1) | 135 (87.1) | |
IB | 393 (11.9) | 373 (11.9) | 20 (12.9) | |
AJCC.T, n (%) | 0.012 | |||
T1a | 1488 (45.2) | 1414 (45.1) | 74 (47.7) | |
T1b | 889 (27) | 836 (26.7) | 53 (34.2) | |
T1NOS | 912 (27.7) | 884 (28.2) | 28 (18.1) | |
Region.nodes, n (%) | 0.055 | |||
0 | 1866 (56.7) | 1788 (57.1) | 78 (50.3) | |
0–10 | 522 (15.9) | 487 (15.5) | 35 (22.6) | |
11–84 | 901 (27.4) | 859 (27.4) | 42 (27.1) | |
Radiotherapy, n (%) | 1 | |||
NO | 2836 (86.2) | 2702 (86.2) | 134 (86.5) | |
YES | 453 (13.8) | 432 (13.8) | 21 (13.5) | |
Chemotherapy, n (%) | 0.668 | |||
NO | 2664 (81) | 2541 (81.1) | 123 (79.4) | |
YES | 625 (19) | 593 (18.9) | 32 (20.6) | |
Surgery.method, n (%) | 0.003 | |||
None | 1282 (39) | 1243 (39.7) | 39 (25.2) | |
biopsy/local excision | 346 (10.5) | 322 (10.3) | 24 (15.5) | |
Others | 590 (17.9) | 557 (17.8) | 33 (21.3) | |
Subtotal& Total resection | 1071 (32.6) | 1012 (32.3) | 59 (38.1) | |
Grade, n (%) | 0.396 | |||
I | 361 (11) | 345 (11) | 16 (10.3) | |
II | 970 (29.5) | 916 (29.2) | 54 (34.8) | |
III | 1263 (38.4) | 1212 (38.7) | 51 (32.9) | |
IV/Unknown | 695 (21.1) | 661 (21.1) | 34 (21.9) | |
Hist.type, n (%) | 0.037 | |||
AC | 2486 (75.6) | 2373 (75.7) | 113 (72.9) | |
Others | 95 (2.9) | 85 (2.7) | 10 (6.5) | |
SRCC | 708 (21.5) | 676 (21.6) | 32 (20.6) | |
Primary.site, n (%) | 0.213 | |||
Cardiac/Gastric fundus | 1445 (43.9) | 1370 (43.7) | 75 (48.4) | |
Gastric antrum/Pylorus | 774 (23.5) | 744 (23.7) | 30 (19.4) | |
Gastric body | 300 (9.1) | 287 (9.2) | 13 (8.4) | |
Greater curvature | 113 (3.4) | 103 (3.3) | 10 (6.5) | |
Lesser curvature | 237 (7.2) | 226 (7.2) | 11 (7.1) | |
Overlapping/NOS | 420 (12.8) | 404 (12.9) | 16 (10.3) |
