Table 2 Analysis of prognostic factors for occurrence of secondary malignant tumour in GC patients by competitive hazard model.
From: Analyzing risk factors for second malignancies in early gastric carcinoma from the SEER database
Variables | Total (n = 3289) | NOSM (n = 1677) | OSM (n = 155) | Death (n = 1457) | p |
|---|---|---|---|---|---|
Age.cat, n (%) | < 0.001 | ||||
18–65 | 1017 (30.9) | 720 (42.9) | 48 (31) | 249 (17.1) | |
66–75 | 944 (28.7) | 532 (31.7) | 54 (34.8) | 358 (24.6) | |
76–100 | 1328 (40.4) | 425 (25.3) | 53 (34.2) | 850 (58.3) | |
Sex, n (%) | 0.345 | ||||
Female | 1220 (37.1) | 624 (37.2) | 49 (31.6) | 547 (37.5) | |
Male | 2069 (62.9) | 1053 (62.8) | 106 (68.4) | 910 (62.5) | |
Race, n (%) | < 0.001 | ||||
White | 2357 (71.7) | 1170 (69.8) | 111 (71.6) | 1076 (73.9) | |
Black | 397 (12.1) | 154 (9.2) | 18 (11.6) | 225 (15.4) | |
Others | 535 (16.3) | 353 (21) | 26 (16.8) | 156 (10.7) | |
Marital, n (%) | < 0.001 | ||||
Married | 1795 (54.6) | 1033 (61.6) | 96 (61.9) | 666 (45.7) | |
Divorced/Separated | 293 (8.9) | 158 (9.4) | 8 (5.2) | 127 (8.7) | |
Single/UnMarried | 385 (11.7) | 184 (11) | 21 (13.5) | 180 (12.4) | |
Widowed/Others | 816 (24.8) | 302 (18) | 30 (19.4) | 484 (33.2) | |
Diagnosis, n (%) | < 0.001 | ||||
2010–2012 | 1644 (50) | 720 (42.9) | 95 (61.3) | 829 (56.9) | |
2013–2015 | 1645 (50) | 957 (57.1) | 60 (38.7) | 628 (43.1) | |
AJCC, n (%) | < 0.001 | ||||
IA | 2896 (88.1) | 1529 (91.2) | 135 (87.1) | 1232 (84.6) | |
IB | 393 (11.9) | 148 (8.8) | 20 (12.9) | 225 (15.4) | |
AJCC.T, n (%) | < 0.001 | ||||
T1a | 1488 (45.2) | 903 (53.8) | 74 (47.7) | 511 (35.1) | |
T1b | 889 (27) | 580 (34.6) | 53 (34.2) | 256 (17.6) | |
T1NOS | 912 (27.7) | 194 (11.6) | 28 (18.1) | 690 (47.4) | |
Region.nodes, n (%) | < 0.001 | ||||
0 | 1866 (56.7) | 604 (36) | 78 (50.3) | 1184 (81.3) | |
0–10 | 522 (15.9) | 357 (21.3) | 35 (22.6) | 130 (8.9) | |
11–84 | 901 (27.4) | 716 (42.7) | 42 (27.1) | 143 (9.8) | |
Radiotherapy, n (%) | < 0.001 | ||||
NO | 2836 (86.2) | 1542 (91.9) | 134 (86.5) | 1160 (79.6) | |
YES | 453 (13.8) | 135 (8.1) | 21 (13.5) | 297 (20.4) | |
Chemotherapy, n (%) | < 0.001 | ||||
NO | 2664 (81) | 1452 (86.6) | 123 (79.4) | 1089 (74.7) | |
YES | 625 (19) | 225 (13.4) | 32 (20.6) | 368 (25.3) | |
Surgery.method, n (%) | < 0.001 | ||||
None | 1282 (39) | 213 (12.7) | 39 (25.2) | 1030 (70.7) | |
biopsy/local excision | 346 (10.5) | 247 (14.7) | 24 (15.5) | 75 (5.1) | |
Others | 590 (17.9) | 411 (24.5) | 33 (21.3) | 146 (10) | |
Subtotal& Total resection | 1071 (32.6) | 806 (48.1) | 59 (38.1) | 206 (14.1) | |
Grade, n (%) | < 0.001 | ||||
I | 361 (11) | 231 (13.8) | 16 (10.3) | 114 (7.8) | |
II | 970 (29.5) | 517 (30.8) | 54 (34.8) | 399 (27.4) | |
III | 1263 (38.4) | 604 (36) | 51 (32.9) | 608 (41.7) | |
IV/Unknown | 695 (21.1) | 325 (19.4) | 34 (21.9) | 336 (23.1) | |
Hist.type, n (%) | 0.009 | ||||
AC | 2486 (75.6) | 1241 (74) | 113 (72.9) | 1132 (77.7) | |
Others | 95 (2.9) | 52 (3.1) | 10 (6.5) | 33 (2.3) | |
SRCC | 708 (21.5) | 384 (22.9) | 32 (20.6) | 292 (20) | |
Primary.site, n (%) | 0.004 | ||||
Cardiac/Gastric fundus | 1445 (43.9) | 733 (43.7) | 75 (48.4) | 637 (43.7) | |
Gastric antrum/Pylorus | 774 (23.5) | 422 (25.2) | 30 (19.4) | 322 (22.1) | |
Gastric body | 300 (9.1) | 157 (9.4) | 13 (8.4) | 130 (8.9) | |
Greater curvature | 113 (3.4) | 57 (3.4) | 10 (6.5) | 46 (3.2) | |
Lesser curvature | 237 (7.2) | 129 (7.7) | 11 (7.1) | 97 (6.7) | |
Overlapping/NOS | 420 (12.8) | 179 (10.7) | 16 (10.3) | 225 (15.4) |
