Table 1 The baseline characteristics of participants.
Characteristic | Q1, N = 45,965 | Q2, N = 45,823 | Q3, N = 45,857 | Q4, N = 45,872 | P value |
|---|---|---|---|---|---|
Age (years) | 39 (33, 48) | 38 (32, 47) | 37 (32, 47) | 36 (31, 50) | < 0.001 |
Gender | < 0.001 | ||||
Male | 24,507 (53%) | 23,875 (52%) | 23,871 (52%) | 25,090 (55%) | |
Female | 21,458 (47%) | 21,948 (48%) | 21,986 (48%) | 20,782 (45%) | |
BMI (kg/m2) | 22.8 (20.5, 25.2) | 22.7 (20.5, 25.0) | 22.5 (20.5, 24.8) | 22.9 (20.8, 25.1) | < 0.001 |
SBP (mmHg) | 111 (103, 122) | 115 (105, 125) | 116 (106, 127) | 124 (113, 135) | < 0.001 |
DBP (mmHg) | 79 (72, 87) | 74 (68, 81) | 70 (65, 77) | 68 (62, 74) | < 0.001 |
PPI (%) | 30 (27.36, 31.71) | 35.34 (34.26, 36.43) | 39.47 (38.46, 40.52) | 44.37 (42.74, 47.18) | < 0.001 |
FPG (mmol/L) | 4.80 (4.41, 5.10) | 4.80 (4.45, 5.10) | 4.82 (4.49, 5.12) | 4.87 (4.54, 5.16) | < 0.001 |
TC (mmol/L) | 4.62 (4.09, 5.22) | 4.60 (4.06, 5.18) | 4.56 (4.01, 5.15) | 4.56 (4.01, 5.17) | < 0.001 |
TG (mmol/L) | 1.07 (0.73, 1.63) | 1.03 (0.71, 1.55) | 1.00 (0.70, 1.49) | 1.01 (0.70, 1.50) | < 0.001 |
QHDL | < 0.001 | ||||
Not recorded | 20,378 (44%) | 20,551 (45%) | 20,961 (46%) | 21,165 (46%) | |
Low | 9070 (20%) | 8429 (18%) | 8139 (18%) | 7848 (17%) | |
Medium | 8309 (18%) | 8423 (18%) | 8367 (18%) | 8388 (18%) | |
High | 8208 (18%) | 8420 (18%) | 8390 (18%) | 8471 (18%) | |
QLDL | < 0.001 | ||||
Not recorded | 20,255 (44%) | 20,462 (45%) | 20,853 (45%) | 20,989 (46%) | |
Low | 8258 (18%) | 8348 (18%) | 8648 (19%) | 8401 (18%) | |
Medium | 8555 (19%) | 8600 (19%) | 8295 (18%) | 8202 (18%) | |
High | 8897 (19%) | 8413 (18%) | 8061 (18%) | 8280 (18%) | |
ALT, U/L | 18 (13, 28) | 17 (12, 27) | 17 (12, 26) | 18 (13, 26) | < 0.001 |
QAST | < 0.001 | ||||
Not recorded | 27,285 (59%) | 27,153 (59%) | 26,775 (58%) | 26,083 (57%) | |
Low | 5965 (13%) | 6357 (14%) | 6720 (15%) | 6366 (14%) | |
Medium | 6245 (14%) | 6174 (13%) | 6372 (14%) | 6618 (14%) | |
High | 6470 (14%) | 6139 (13%) | 5990 (13%) | 6805 (15%) | |
BUN (mmol/L) | 4.48 (3.78, 5.29) | 4.47 (3.75, 5.29) | 4.49 (3.77, 5.30) | 4.56 (3.82, 5.40) | < 0.001 |
Scr (μmol/L) | 69 (57, 80) | 68 (57, 80) | 68 (57, 80) | 70 (58, 81) | < 0.001 |
Smoking | < 0.001 | ||||
Not recorded | 32,495 (71%) | 33,281 (73%) | 33,360 (73%) | 33,540 (73%) | |
Current | 2746 (6.0%) | 2487 (5.4%) | 2297 (5.0%) | 2107 (4.6%) | |
Ever | 553 (1.2%) | 516 (1.1%) | 507 (1.1%) | 528 (1.2%) | |
Never | 10,171 (22%) | 9539 (21%) | 9693 (21%) | 9697 (21%) | |
Drinking | < 0.001 | ||||
Not recorded | 32,495 (71%) | 33,281 (73%) | 33,360 (73%) | 33,540 (73%) | |
Current | 269 (0.6%) | 273 (0.6%) | 237 (0.5%) | 205 (0.4%) | |
Ever | 1851 (4.0%) | 1796 (3.9%) | 1857 (4.0%) | 1847 (4.0%) | |
Never | 11,350 (25%) | 10,473 (23%) | 10,403 (23%) | 10,280 (22%) | |
Family history of diabetes | 1015 (2.2%) | 945 (2.1%) | 902 (2.0%) | 772 (1.7%) | < 0.001 |