Figure 5 | Scientific Reports

Figure 5

From: Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data

Figure 5

WGCNA to identify hub modules and hub genes based on healthy control and active UC. (A) Selection of the soft-thresholding powers. The left panel shows the relationship between soft-thresholding powers and scale free topology model fit, while the right shows the relationship between soft-thresholding powers and mean connectivity. (B) Module clustering dendrogram based on a dissimilarity measure (1-TOM). Different modules are colored differently. (C) Heatmap of the correlation between each module and trait. Red and blue indicates a positive or negative correlation, respectively. The darker the color, the stronger the correlation. (D) Scatter plot of the relationship between module membership (MM) and gene significance (GS) in red module. Genes in right upper quadrant are identified as hub genes in red module.

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