Table 3 Functional motor and sensory assessments, and nerve conduction.

From: Central neurodegeneration in Kennedy’s disease accompanies peripheral motor dysfunction

 

SBMA (n = 12)

Normative range (mean; SD)

Abnormal (%)

Hand grip strength (kg)a

 Left

14.5 (5.2)

39.7 ± 11.8

58

 Right

19.5 (10.2)

41.4 ± 12.4

50

Grooved pegboard time (s)b

93.9 (16.4)

69.9 ± 12.5

58

Grating orientation threshold (mm)c

6.9 (2.4)

2.8 ± 0.29

92

Nerve conduction [motor]d

 [Upper] Right median CMAP (mV)

7.1 (3.1)

15.8 ± 5.9

42

 [Lower] Right tibial CMAP (mV)

4.3 (1.6)

14.1 ± 6.2

42

Nerve conduction [sensory]d

 [Upper] Right median SNAP (μV)

10.5 (8.1)

31.4 ± 10.9

100

 [Lower] Right sural SNAP (μV)

3.6 (2.2)

22.4 ± 11

17

  1. Published normative values across assessments and percentage of SBMA patients with abnormal performance (≥ 2 SD from mean).
  2. *Compound muscle action potential (CMAP); antidromic sensory nerve action potential (SNAP).
  3. **Reference normative value ranges: (a) Wang et al.26, (b) Ruff and Parker27, (c) Tremblay et al.28, (d) Ma and Liveson19.
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