Figure 6
Potency of the identified compounds. MCF7 and A375 cells were exposed for 24 h or 72 h with the candidate compounds and bortezomib as a reference. (A,B) After 24 h, the most potent drugs for MCF7 cells were puromycin dihydrochloride and tegaserod maleate, and after 72 h all drugs were potent except for manumycin-A. (C,D) For A375 cells, the drug potency varied for the candidate compounds after 24 h treatment, whereas all compounds were potent but often at high concentration after 72 h. Error bars depict the standard deviation.
