Figure 4
From: C-Mannosyl tryptophan is a novel biomarker for thrombocytosis of myeloproliferative neoplasms
(A) Comparison of representative serum samples from T-MPN patient with MF-2 (thin line) versus T-MPN patient with MF-0 (dotted line). The serum CMW levels were quantified using UPLC. The arrow indicates a peak corresponding to CMW. (B) Serum CMW levels of patients with MF-0/1 (n = 11) and with MF-2/3 (n = 7). The circles show CMW levels, and red line shows the medians. (C) Serum CMW levels of patients with MF-0 (n = 6) and with MF-1/2/3 (n = 12). (D) The ROC curve of serum CMW levels for diagnosing T-MPN with MF-1/2/3. The AUC was 0.875; sensitivity, 0.750; and specificity, 1.000. Based on these values, the CMW cutoff value was 517.9 nM. ns; not significant. **p < 0.01.
