Figure 1

Clinical presentations in patients with atopic eyelid dermatitis. Legend: The representative images of three patients with adult-onset atopic eyelid dermatitis (AED) (Patients 1–3), who are under care at the Department of Dermatology and Venereology (Head—Prof. Olga Olisova), I.M. Sechenov First Moscow State Medical University: patient 1 (A,D,H), aged 32 (an AED onset at 30 years), patient 2 (B,E,I), aged 37 (an AED onset at 37 years), patient 3, (C,F,J) aged 31 (an AED onset at 21 years). Facial skin imaging was carried out using the AI face recognition technology, 8-spectrum imaging technology and deep quantitative analysis by Capricorn Intelligent Imager ZMLH01 (Beijing Sincoheren S&T Development, Beijing, China). The high-definition images were acquired in a negatively polarized UV light (365 nm, A-F), white light (RGB, range 420–620 nm, H-J). AED patients presented with symmetrical, scaly erythematous periorbital areas with a hyperpigmentation and a lichenification, particularly pronounced at the medial aspects of the upper and lower eyelids. Informed consents from the AED patients for a publication of these images were obtained.