Figure 2
From: Eyelid dermatitis in patch-tested adult patients: a systematic review with a meta-analysis











(A-Q) Forest plots for demographic and clinical characteristics of patients with eyelid dermatitis. Legend: The proportional meta-analyses [random-effects] were carried out for female patients (A) and patients aged 40 years or older (B) in the studies including the patients with eyelid dermatitis. The proportion of atopic eyelid dermatitis in the studies with patients with eyelid dermatitis (C) was estimated at 27.5% (95% CI 0.177, 0.384). The differential diagnosis of eyelid dermatitis includes eyelid allergic contact dermatitis (D), seborrheic dermatitis (E), psoriasis (F), and irritant contact dermatitis (G). H–N represent proportional meta-analyses for contact sensitizations to nickel (positive patch tests and clinically relevant reactions), gold, thimerosal, neomycin, and corticosteroids (budesonide and toxicortol), respectively. Clinically, the proportion of isolated eyelid dermatitis (O) of 8453 ED patients was 51.6% [95% CI 0.408, 0.623] whereas the proportion of isolated atopic eyelid dermatitis (P) of the patients with atopic dermatitis with an eyelid involvement was 26.9% [95% CI 0.117, 0.449].