Figure 1

Stable knockdown of lncTCF7 validated its role in TCF7 transcription regulation. (A) qRT-PCR analysis of lncTCF7 knockdown by two independent, stably expressed shRNAs in U251 cells. (B) WNT signaling pathway protein TCF7 expression loss, analyzed by qRT-PCR. Data are shown as average relative knockdown ± SEM (two-tailed ratio t-test, n = 3, *P-value < 0.05).