Table 3 The comparative investigation of synthesizing the Isoxazol-5-one/Pyrazol-3-one scaffold using the current method with reported methods.

From: Highly efficient synthesis of isoxazolones and pyrazolones using g-C3N4·OH nanocomposite with their in silico molecular docking, pharmacokinetics and simulation studies

S. no.

Catalyst

Condition

Time

Yield (%)

Reference

1

Fe3O4@MAP-SO3H NPs (20 mg)

EtOH-H2O, 25 °C, U.S.

20-30 min

85-92

40

2

DMAP, (8 mol%)

EtOH:H2O (1:1)

20-80 min

86-98

41

3

Sulfamic acid (15 mol%)

EtOH:H2O (1:1), reflux

1-4 h

58-92

42

4

CuI@Met-β‐ CD (2%wt)

Water, 50 °C

1-20 min

80-97

43

5

Piperidine (1 mL)

EtOH, R.T.

24 h

70-97

44

6

g-C3N4·OH (15 mg)

Water, R.T.

25-45 min

89-97

This work

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