Figure 21
From: Simulation of CRISPR-Cas9 editing on evolving barcode and accuracy of lineage tracing
Lineage tree reconstruction. (A) Leaf barcodes are sequenced and aligned, and their order is random. (B) Leaf barcodes are paired and parent nodes are rebuilt. (C) Parent barcodes are filtered by the root barcode so that gradually they converge to the root. (D) The rebuilding process continues retrospectively until the root node is reached.
