Figure 2

Frequency maps of abnormalities in individual AD subjects (compared with HEC). For display purposes, the contrast showing deficits in individual patients (SPM t map) was thresholded at voxel-level p < 0.01 (uncorrected) and binarized such that significant voxels were assigned the value of 1 (all remaining voxels set to 0). Thresholded t maps were combined by summing up; hence, for each modality a deficit map with theoretically possible values from 0 to 26 was obtained. The lower threshold for display was arbitrarily set to voxels with significant abnormality in at least five patients.