Table 2 Death, age-standardized death rates, and time trend from 2010 to 2019 of primary liver cancer during 2010 to 2019 in the Asia–Pacific region, stratified by sex and etiology.

From: Changes in the epidemiological trends of primary liver cancer in the Asia–Pacific region

 

Southeast Asia

Western Pacific

2019 Death (95% UI)

2019 Age-standardized Death rate

per 100,000 (95% UI)

APC from 2010 to 2019

(95% CI)

p

2019 Death (95% UI)

2019 Age-standardized Death rate

per 100,000 (95% UI)

APC from 2010 to 2019

(95% CI)

p

Overall

70,000 (60,600 to 80,600)

4.22 (3.67 to 4.84)

−0.48 (−0.69 to −0.27)

 < 0.001

254,100 (221,700 to 289,500)

9.50 (8.31 to 10.78)

−0.29 (−0.64 to 0.06)

0.109

By sex

  Male

46,500 (39,800 to 54,400)

5.74 (4.90 to 6.72)

−0.27 (−0.43 to −0.11)

0.001

183,200 (153,400 to 216,500)

14.51 (12.26 to 16.98)

0.04 (−0.39 to 0.48)

0.847

  Female

23,500 (19,500 to 28,100)

2.80 (2.31 to 3.34)

−0.66 (−1.07 to −0.24)

0.002

70,800 (59,300 to 82,500)

4.97 (4.17 to 5.79)

−1.12 (−1.25 to −0.98)

 < 0.001

By etiology

  Alcohol

18,600 (14,400 to 23,400)

1.11 (0.86 to 1.39)

0.17 (−0.14 to 0.47)

0.294

27,600 (21,300 to 34,700)

1.00 (0.78 to 1.25)

0.54 (0.20 to 0.89)

0.002

  Hepatitis B

25,300 (20,200 to 31,300)

1.43 (1.14 to 1.76)

−1.12 (−1.27 to −0.97)

 < 0.001

134,500 (111,400 to 161,500)

4.96 (4.11 to 5.93)

0.02 (−0.50 to 0.53)

0.951

  Hepatitis C

16,000 (12,600 to 19,700)

1.06 (0.83 to 1.29)

−0.37 (−0.58 to −0.17)

 < 0.001

65,700 (56,500 to 74,100)

2.53 (2.17 to 2.85)

−1.36 (−1.51 to −1.21)

 < 0.001

  MASLD

7200 (5500 to 9300)

0.46 (0.35 to 0.59)

0.09 (−0.10 to 0.28)

0.305

13,400 (10,900 to 16,400)

0.50 (0.41 to 0.61)

0.91 (0.54 to 1.28)

 < 0.001

  Others

3000 (2400 to 3700)

0.17 (0.14 to 0.21)

−0.56 (−0.88 to −0.25)

 < 0.001

12,800 (10,400 to 15,500)

0.50 (0.41 to 0.60)

−0.13 (−0.82 to 0.56)

0.708

  1. Abbreviation: CI: confidence interval, MASLD: metabolic dysfunction-associated steatotic liver disease, UI: uncertainty interval.
  2. *Significant values are in bold.