Fig. 4
From: Multiple endocrine defects in adult-onset Sprouty1/2/4 triple knockout mice
Phosphaturia and hypophosphatemia in 3KO mice. (a) Biochemical analysis of urine metabolites. CATR calcium-to-creatinine ratio, PTCR phosphate-to-creatinine ratio, MATCR microalbumin-to-creatinine ratio. (b) Hypophosphatemia with normal calcium plasma levels of 3KO mice (left and central panels). Right panels show that low phosphorus plasma levels cannot be attributed to abnormally elevated circulating levels of FGF23. Graphs (a) and (b) represent means ± SD; significance (ns P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001) was determined using t test (a) and two-way ANOVA (b).
