Fig. 4

CRC-association scores predict microbiome-induced tumorigenicity. (A) CRC-association scores and underlying Wald metrics of genome-aligned CAGs for a panel of bacterial strains. Consortium members highlighted. (B) CRC-or-health signatures seen in metagenomic sequencing of fecal pellets collected from gnotobiotic mice colonized with CRC-associated or health-associated consortia. (C) Small intestinal tumor burden in gnotobiotic mice colonized with CRC-associated consortium or health-associated consortium.