Table 1 Baseline characteristics.
T-TEER (n = 32) | PA (n = 52) | p Value | |
|---|---|---|---|
Female, n (%) | 19 (59) | 34 (65) | 0.579 |
Age, years (IQR) | 82 (78–84) | 81 (77–83) | 0.287 |
BMI, kg/m2 (IQR) | 24 (22–27) | 25 (22–28) | 0.235 |
EUROScore II (IQR) | 5.6 (3.5–8.7) | 4.5 (3.0–8.4) | 0.261 |
NYHA class | 0.112 | ||
I, n (%) | 0 (0) | 0 (0) | |
II, n (%) | 2 (6) | 8 (15) | |
III, n (%) | 25 (78) | 40 (77) | |
IV, n (%) | 5 (16) | 4 (8) | |
Leading cause of TR | 0.131 | ||
Primary TR, n (%) | 1 (3) | 1 (2) | |
Atrial TR, n (%) | 24 (75) | 28 (54) | |
Ventricular TR, n (%) | 6 (19) | 22 (42) | |
CIED-related TR, n (%) | 1 (3) | 0 (0) | |
Mixed pathology, n (%) | 0 (0) | 1 (2) | |
Coronary artery disease, n (%) | 12 (38) | 30 (58) | 0.072 |
CIED, n (%) | 11 (34) | 14 (27) | 0.468 |
Atrial fibrillation or flutter, n (%) | 28 (88) | 50 (96) | 0.135 |
Arterial hypertension, n (%) | 26 (81) | 45 (87) | 0.515 |
Diabetes mellitus, n (%) | 4 (13) | 16 (31) | 0.082 |
Stroke, n (%) | 8 (25) | 9 (17) | 0.394 |
Peripheral artery disease, n (%) | 9 (28) | 2 (4) | 0.001 |
Chronic obstructive pulmonary disease, n (%) | 9 (28) | 9 (17) | 0.241 |
History of surgical or percutaneous valve therapy, n (%) | 14 (44) | 18 (35) | 0.402 |
Serum creatinine, mg/dl (IQR) | 1.3 (1.0–1.7) | 1.3 (1.0–1.4) | 0.652 |
NT-proBNP, ng/l (IQR) | 1919 (1062–3775) | 2463 (1711–4206) | 0.191 |
Bilirubin, mg/dl (IQR) | 1.0 (0.6–1.6), n = 26 | 0.6 (0.5–1.1), n = 33 | 0.145 |
Systolic PAP, mmHg ± SD | 38 ± 14, n = 23 | 41 ± 13, n = 24 | 0.521 |
Heart failure therapy | |||
Diuretics, n (%) | 31 (97) | 51 (98) | 0.726 |
Beta-blocker, n (%) | 29 (91) | 43 (83) | 0.313 |
ACE inhibitor or sacubitril/valsartan, n (%) | 22 (69) | 42 (81) | 0.209 |
Mineralocorticoid receptor antagonist, n (%) | 20 (63) | 31 (60) | 0.793 |
SGLT2 inhibitor, n (%) | 13 (41) | 10 (19) | 0.033 |