Fig. 1
From: Identification of genetic variants associated with clinical features of sickle cell disease
Regional plots of the four genome-wide significant loci associated with clinical phenotypes of SCD using LocusZoom42 listed in the GTEx portal. Purple diamond indicates the most significantly associated SNP, and circles represent the other SNPs in the region, with coloring from blue to red corresponding to r2 values from 0 to 1 with the index SNP. (A) Hemoglobin F, 15q14; (B) acute chest syndrome: 15q26.1; (C) pain, 2p25.1; (D) pain, 15q26.3. All images in the figures were generated using a combination of R and PowerPoint. The data visualizations and analyses were conducted using R (version 4.3.1), which can be accessed at https://www.r-project.org/. The final assembly and labeling of the figures were completed using Microsoft PowerPoint (Microsoft 365 version).
