Table 1 Demographic and clinical characteristics of the study cohort.
From: Identification of genetic variants associated with clinical features of sickle cell disease
Characteristic | N = 5201 |
|---|---|
Demographics | |
Age at first encounter | 1.5 (0.6, 7.2) |
Age at last encounter | 17 (11, 22) |
Patient gender | |
Female | 238 (48%) |
Male | 258 (52%) |
Patient ancestry | |
Black or African American | 369 (97%) |
Other | 8 (2.1%) |
White | 2 (0.5%) |
Declined to answer | 1 (0.3%) |
Medical history | |
Asthma | 197 (39%) |
Past or current inhaled corticosteroid use | 135 (26%) |
Past or current hydroxyurea use | 410 (80%) |
Past or current chronic transfusion | 145 (28%) |
Acute chest syndrome rate, per year | 0.09 (0.00, 0.24) |
Vaso-occlusive episode rate, per year | 0.50 (0.15, 1.33) |
Pain episode rate, per year | 0.52 (0.16, 1.36) |
Admissions, per year | 1.14 (0.58, 2.11) |
1Median (IQR); n (%) | |