Table 2 Statistical comparison of the results obtained by the proposed method and the reported method for the determination of DIP and HBB in the dosage form.

From: “Eco-friendly HPLC method for analysis of dipyrone and hyoscine in different matrices with biomonitoring”

Parameters

DIP

HBB

Proposed method

Reported method**38

Proposed method

Reported method**38

Mean***

98.42

99.31

100.16

99.92

SD

0.39

0.82

1.54

1.20

Variance

0.15

0.67

2.37

1.44

n

5

5

5

5

F value (6.39) *

4.48

1.65

Student t-test (2.306) *

2.198

0.275

  1. *Values between parenthesis are the theoretical value of t and F at P = 0.05 and n = 5.
  2. **HPLC method using C18 (250 mm × 4.6 mm) mobile phase composed of (water: methanol, 50:50) pH adjusted to 7 using triethylamine and trifluoracetic acid UV detection 210 nm 38.
  3. ***Percentage recoveries of 5 determinations.