Fig. 3
From: Inhibition of miR-194-5p avoids DUSP9 downregulation thus limiting sepsis-induced cardiomyopathy
Effects of miR-194-5p knockdown or overexpression on mitochondrial function and oxidative stress in hearts from sepsis-challenged mice. (a) Representative transmission electron micrographs of left ventricular specimens, n = 4 in each group. (b) and (c) ATP content and citrate synthase (CS) in mitochondria isolated from mice, n = 4 in each group. (d) Mitochondrial calcium retention capacity (mCRC), n = 4 in each group. (e) and (f) Reactive oxygen species (ROS) and malondialdehyde (MDA) levels, n = 4 in each group. *P < 0.05 versus control, #P < 0.05 versus LPS, $P < 0.05 versus LPS + antagomir control, &P < 0.05 versus LPS + agomir control.
