Figure 4

Characterization of ETD-PHs-HA gel, ETD loaded HA gel, and HA gel. (A) Shear stress vs. viscosity plot (B) Shear stress vs. shear rate plot; (C) Comparison of spreadability profiles at different weights (g), (D) In-vitro ETD release profiles from Phosalosomes formulations (ETD-PHs), with different loading concentrations compared to free drug in PB (pH 5.5), and (E) In-vitro ETD release profiles from ETD-loaded phosalosomes-HA (ETD-PHs-HA) gel in PBS (pH 7.4) and PB (pH5.5) at 32 ± 0.5 °C for 24 h using dialysis-bag method.