Table 2 Calculated permeation parameters of ETD suspension, ETD Phosalosomes (ETD-PHs) and ETD phosalosomes- HA (ETD-PHs-HA) gel.

From: Follicular mediated etodolac phosalosomal gel for contact dermatitis alleviation, insights from optimization to in-vivo appraisal

Sample

Flux (µg/cm2.h)

Lag time (h)

Skin surface concentration (C0, µg/cm3)

Diffusion coefficient (D, cm2/s)

ETD suspension

0.868

1.014

5.284*103

4.564*10–11

ETD-PHs

1.111

0.333

5.221*103

6.389*10–11

ETD-PHs-HA gel

1.374

0.639

5.274*103

7.237*10–11