Fig. 3

The landscape of immune infiltration between CRC and normal groups. (A) Relative percentages of 22 immune cells across all samples. (B) Heatmap showing the correlation of infiltration of 22 immune cell types. The colored squares represent the strength of the correlation; red represents a positive correlation, whereas purple represents a negative correlation. The deeper the color is, the stronger the correlation is. (C) Differences in immune cell content between normal patients (blue) and patients with CRC (yellow). P < 0.05 was considered to indicate statistical significance. (D–H) Spearman correlations of BCL10 (D), CDKN2A (E), DAPK1 (F), PYGM (G), and TIMP1 (H) gene expression with immune cell content.