Table 4 Effect allele, effect size and p-values reported by the 4 GWAS studies of AD for the 3 SNPs identified as eQTLs associated with TAS2R41 and TAS2R60. Two of the SNPs are not reported by Marioni et al.
GWAS study | GWAS stats/info | rs11762262 | rs11771145 | rs10228407 |
|---|---|---|---|---|
Wightman et al. PMID 34,493,870 | log Odds | − 0.07 | − 0.05 | 0.06 |
P-Value | 9.80e-08 | 3.81e-07 | 2.71e-08 | |
Mapped Gene (location) | EPHA1-AS1 (intron) | EPHA1-AS1 (intron) | EPHA1-AS1 (intron) | |
Effect allele reported | T | A | T | |
Marioni et al. PMID 29,777,097 | log Odds | Not reported | Not reported | 0.05 |
P-Value | Not reported | Not reported | 1.28e-09 | |
Mapped Gene (location) | Not reported | Not reported | EPHA1-AS1 (intron) | |
Effect allele reported | Not reported | Not reported | T | |
Bellenguez et al. PMID 35,379,992 | Odds-Ratio | 0.94 | 0.94 | 1.05 |
P-Value | 6.35e-10 | 1.29e-12 | 1.24e-10 | |
Mapped Gene (location) | EPHA1-AS1 (intron) | EPHA1-AS1 (intron) | EPHA1-AS1 (intron) | |
Effect allele reported | T | A | T | |
Jansen et al. PMID 30,617,256 | log Odds | -0.016 | -0.011 | -0.01 |
P-Value | 5.22e-09 | 8.84e-07 | 9.33e-06 | |
Mapped Gene (location) | EPHA1-AS1 (intron) | EPHA1-AS1 (intron) | EPHA1-AS1 (intron) | |
Effect allele reported | T | A | G |
