Table 5 eQTL analysis results for the 3 SNPs associated with AD in multiple GWAS studies.
SNP/eQTL | Chr | Position (GRCh38) | Location | mRNA | Beta | P-Value (raw) | P-Value (adjusted) | Allele tested (Minor Allele) | MAF |
|---|---|---|---|---|---|---|---|---|---|
rs11762262 | 7 | 143,410,783 | 67.1 kb upstream | TAS2R41 | -0.07 | 9.45e-04 | 1.99e-02 | A | 0.21 |
rs11771145 | 7 | 143,413,669 | 64.2 kb upstream | TAS2R41 | -0.15 | 2.58e-21 | 3.39e-19 | G | 0.43 |
rs11771145 | 7 | 143,413,669 | 29.8 kb upstream | TAS2R60 | -0.33 | 3.26e-27 | 5.77e-25 | G | 0.43 |
rs10228407 | 7 | 143,430,678 | 12.8 kb upstream | TAS2R60 | -0.31 | 7.40e-24 | 1.05e-21 | A | 0.46 |
rs10228407 | 7 | 143,430,678 | 47.2 kb upstream | TAS2R41 | -0.15 | 5.11e-20 | 6.40E-18 | A | 0.46 |
