Table 1 Sociodemographic, comorbidities and genetic analysis association data with disease severity.
From: Correlating COVID-19 severity with biomarker profiles and patient prognosis
Sociodemographic factors | N = 226 | % | P-value | |
|---|---|---|---|---|
Clinical spectrum | Mild | 60 | 26.5 | – |
Moderate | 65 | 28.7 | ||
Severe | 101 | 44.6 | ||
Sex | Male | 110 | 48.6 | 0.06 |
Female | 116 | 51.3 | ||
Age group | Under 39 years | 69 | 30.5 | < 0.001 |
40–49 years | 61 | 27.0 | ||
Above 50 years | 96 | 42.5 | ||
Schooling | No higher schooling | 84 | 37.2 | < 0.001 |
Higher schooling | 142 | 62.8 | ||
Ethnic Group | White | 141 | 62.4 | 0.003 |
Non-white | 85 | 37.6 | ||
BMI classification | Normal | 53 | 23.4 | < 0.001 |
Overweight | 21 | 9.3 | ||
Obesity I | 129 | 57.0 | ||
Obesity II | 16 | 7.0 | ||
Obesity III | 7 | 3.1 | ||
Physical activities | No | 119 | 52.6 | 0.43 |
Yes | 107 | 47.4 | ||
Presence of post-COVID-19 sequelae | No | 59 | 26.1 | < 0.001 |
Yes | 167 | 73.9 | ||
Comorbidities | N = 226 | % | P-value | |
|---|---|---|---|---|
Chronic lung disease | No | 201 | 88.9 | 0.43 |
Yes | 25 | 11.1 | ||
Chronic cardiovascular disease | No | 157 | 69.5 | 0.002 |
Yes | 69 | 30.5 | ||
Diabetes mellitus | No | 195 | 86,3 | 0.006 |
Yes | 31 | 13.7 | ||
History of neoplasia | No | 204 | 90.3 | 0.20 |
Yes | 22 | 9.7 |
Minimum | Maximum | Median | Mean (± SD) | |
|---|---|---|---|---|
Age (years) | 19 | 72 | 47.5 | 46.9 (12.3) |
BMI (kg/m2) | 18.1 | 51.6 | 27.3 | 28.4(5.3) |
Genetic analysis | N = 226 | % | P-value | |
|---|---|---|---|---|
Blood typing | Not O group | 117 | 51.8 | 0.78 |
O group | 109 | 48.2 | ||
Variant hemoglobin* | AA | 213 | 94.2 | 0.81 |
AC | 1 | 0.4 | ||
AS | 9 | 4.0 | ||
TNFA rs1800629 | A/G | 57 | 25.2 | 0.69 |
A/A | 2 | 0.9 | ||
G/G | 167 | 73.9 | ||
IL-6 rs1800795 | C/G | 101 | 44.7 | 0.38 |
C/C | 17 | 7.5 | ||
G/G | 108 | 47.8 | ||
FV rs6025 | C/C | 223 | 98.7 | > 0.99 |
C/T | 3 | 1.3 | ||
FII rs1799963 | A/G | 6 | 2.7 | 0.70 |
G/G | 220 | 97.3 | ||
MTHFR rs1801133** | C/C | 107 | 48.4 | 0.035 |
C/T | 95 | 43.0 | ||
T/T | 19 | 8.6 |
