Table 2 Relationship between quantitative hemostatic/inflammatory parameters and the clinical spectrum of covid-19.

From: Correlating COVID-19 severity with biomarker profiles and patient prognosis

Biomarker

Groups

P-value

Fibrinogen (mg/dL)

Mild

1

Moderate

 > 0.99

Severe

0.39

Factor VIII (%)

Mild

1

Moderate

0.49

Severe

0.046*

Von Willebrand Factor (%)

Mild

1

Moderate

0.76

Severe

0.035*

Dimer D (µg/L)

Mild

1

Moderate

0.42

Severe

0.002 **

IL-6 (pg/mL)

Mild

1

Moderate

0.95

Severe

 > 0.99

TNF-ɑ (pg/mL)

Mild

1

Moderate

0.98

Severe

0.68

Platelet (plaq/mm3)

Mild

1

Moderate

0.67

Severe

 > 0.99

Anticardiolipin IgG (GPL-U/ml)

Mild

1

Moderate

0.06

Severe

0.53

Anticardiolipin IgM (MPL-U/ml)

Mild

1

Moderate

0.818

Severe

 > 0.99

Anti-B2 glycoprotein I IgG (GPL-U/ml)

Mild

1

Moderate

 > 0.99

Severe

0.25

Anti-B2 glycoprotein I IgM (GPL-U/ml)

Mild

1

Moderate

0.56

Severe

 > 0.99

Lupus anticoagulant (absence/ presence)

Mild

0.05

Moderate

Severe

Free S protein (%)

Mild

1

Moderate

0.14

Severe

0.011*

Thrombin time (TT)

Mild

1

Moderate

0.86

Severe

 < 0.001***

Activated partial thromboplastin time (R)

Mild

1

Moderate

 > 0.99

Severe

 > 0.99

Prothrombin time (INR)

Mild

1

Moderate

0.006**

Severe

0.008**

Glycated hemoglobin (%)

Mild

1

Moderate

0.25

Severe

 < 0.001***

  1. The data was analyzed using non-parametric test, multiple comparison Dunn-type test. The P-values were adjusted with multiplicities between symptoms with Bonferroni correction, significant statistic comparatives values are indicated with asterisks: * ≤ 0.05; ** < 0.01; *** < 0.001. The Chi2 test or the exact of Fisher were used in analyses of Lupus anticoagulant.
  2. Significant values are given in bold.