Fig. 5
From: Metformin modulates the TXNIP-NLRP3-GSDMD pathway to improve diabetic bladder dysfunction
The expression and localization of TXNIP, NLRP3, and GSDMD in mice bladder tissue. (A) Immunofluorescence expression of TXNIP in bladder tissue (green represents TXNIP, blue represents DAPI); (B) Immunofluorescence expression of NLRP3 in bladder tissue (green represents NLRP3, blue represents DAPI); (C) Immunohistochemistry of GSDMD in bladder tissue; (D) Western blot expression of NLRP3, TXNIP, and GSDMD. (E–G) Statistical results of NLRP3, TXNIP, and GSDMD. (All statistical results are presented as mean ± SD, n = 8, comparisons between DBD and Control groups, as well as Metformin group, *P < 0.05).
