Fig. 5

PIK3CAmut clusters exhibit distinct receptor/ligand signaling behavior. (a) Heatmaps of sender patterns of clusters show three predominant cell patterns (left) corresponding to ligand-mediated communications (right) from keratinocytes, PIK3CAwt, and PIK3CAmut clusters respectively. (b) Heatmaps of receiver cell patterns (left) and receptor-mediated communication patterns (right) showing the relative contribution of cell clusters to the microenvironment.