Fig. 3 | Scientific Reports

Fig. 3

From: Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex

Fig. 3

Inhibition of fibrin formation induced by endothelial-bound IIa by ATH and AT+H. IIa was incubated in HUVEC-coated wells, followed by removal of excess unbound IIa. A mixture of purified fibrinogen, CaCl2 and AT+H or ATH was added and fibrin formation monitored as in Fig. 2. Final inhibitor (AT or ATH) concentrations are indicated in the X-axis, and the molar ratio of H:AT in the AT+H mixture was 23:1. Data represent mean  ±  SEM (n=5).

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