Fig. 4
From: Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex
Inhibition of fibrin formation induced by IIa bound to HS or TM by ATH and AT+H. IIa was mixed with excess HS (a) or TM (b) before fibrin formation assays were conducted as described in Fig. 2, but in the absence of endothelium. Final inhibitor (AT or ATH) concentrations are indicated in the X-axis, and the molar ratio of H:AT in the AT+H mixture was 23:1. Data represent mean  ± SEM (n=4). The P values are for the indicated comparisons performed by two-way ANOVA, reflecting the significant main effect of anticoagulant. *p(ATH vs. AT+H) = 0.0023. **p(ATH vs. AT+H) = 0.0103.
