Fig. 2 | Scientific Reports

Fig. 2

From: Elevated α-1,2-mannosidase MAN1C1 in glioma stem cells and its implications for immunological changes and prognosis in glioma patients

Fig. 2

MAN1C1 is highly expressed in GBM and correlated to poor prognosis of glioma patients. (A) MAN1C1 mRNA expression and clinical features in the TCGA dataset (n = 669); (B) Raincloud plot of MAN1C1 expression in GBM and LGG patients. (C) Flow chart showing the patient population in the TCGA and CGGA cohorts; (D,E) Univariate and multivariate Cox proportional hazards regression analysis of variables influencing overall patient survival in the TCGA dataset. (F,G) Kaplan–Meier analysis of glioma patients with MAN1C1 High/Low expression in (F) training and (G) test set in the TCGA dataset. (H,I) ROC curve and the risk score distribution stratified by MAN1C1 High/Low expression in (H) training and (I) test set in the TCGA dataset.

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