Table 3 Logistic regression models were used to calculate odds ratios (OR) of prevalence for each comorbidity (dependent variable) according to the presence or absence of breast cancer in men (independent variable).
From: Unveiling the comorbidity burden of male breast cancer
Comorbidity | Prevalence | Crude OR | Adjusted OR1 | p-value2 |
|---|---|---|---|---|
(n, %) | (95% CI) | (95% CI) | ||
Disorders of lipid metabolism | 58 (55.24) | 2.46 (1.67-3.62) | 1.38 (0.94-2.04) | 0.104 |
Hypertension | 52 (49.52) | 1.91 (1.30-2.79) | 0.62 (0.41-0.93) | 0.019* |
Other nutritional; endocrine; and metabolic disorders | 34 (32.38) | 1.87 (1.24-2.82) | 1.15 (0.76-1.73) | 0.509 |
Diabetes Mellitus | 30 (28.57) | 2.6 (1.70-3.98) | 1.26 (0.81-1.93) | 0.303 |
Anxiety disorders | 22 (20.95) | 1.66 (1.04-2.66) | 1.65 (1.03-2.65) | 0.036* |
Cardiac dysrhythmias | 21 (20.00) | 3.25 (2.02-5.25) | 1.43 (0.88-2.34) | 0.150 |
Genitourinary symptoms and ill-defined conditions | 21 (20.00) | 3.98 (2.47-6.42) | 1.48 (0.89-2.44) | 0.129 |
Osteoarthritis | 21 (20.00) | 2.36 (1.46-3.80) | 1.01 (0.62-1.64) | 0.982 |
Cataract | 17 (16.19) | 2.15 (1.28-3.61) | 0.80 (0.47-1.37) | 0.415 |
Obesity | 17 (16.19) | 1.75 (1.04-2.94) | 1.48 (0.88-2.49) | 0.141 |
Hyperplasia of prostate | 16 (15.24) | 1.78 (1.05-3.03) | 0.65 (0.37-1.12) | 0.119 |
Other ear and sense organ disorders | 14 (13.33) | 1.62 (0.92-2.85) | 1.14 (0.65-2.00) | 0.652 |
Coagulation and hemorrhagic disorders | 13 (12.38) | 2.83 (1.58-5.05) | 1.25 (0.69-2.25) | 0.462 |
Thyroid disorders | 12 (11.43) | 2.42 (1.33-4.41) | 1.81 (0.99-3.31) | 0.053 |
Acute myocardial infarction | 12 (11.43) | 2.5 (1.37-4.56) | 1.13 (0.61-2.08) | 0.695 |
Depression and mood disorders | 12 (11.43) | 1.21 (0.66-2.20) | 0.86 (0.47-1.57) | 0.621 |
Glaucoma | 10 (9.52) | 2.04 (1.06-3.92) | 0.95 (0.49-1.83) | 0.876 |
Chronic obstructive pulmonary disease and bronchiectasis | 10 (9.52) | 1.76 (0.92-3.38) | 0.73 (0.37-1.41) | 0.342 |
Osteoporosis | 10 (9.52) | 9.08 (4.73-17.42) | 4.26 (2.2-8.24) | 0.000* |
Delirium, dementia, and amnestic and other cognitive disorders | 10 (9.52) | 1.82 (0.95-3.50) | 0.82 (0.42-1.58) | 0.550 |
Chronic kidney disease | 9 (8.57) | 2.11 (1.07-4.18) | 0.82 (0.41-1.65) | 0.582 |
Gout and other crystal arthropathies | 8 (7.62) | 1.63 (0.79-3.34) | 0.85 (0.41-1.75) | 0.656 |
Blindness and vision defects | 8 (7.62) | 0.92 (0.45-1.90) | 1.10 (0.53-2.26) | 0.797 |
Congestive heart failure; nonhypertensive | 8 (7.62) | 2.75 (1.34-5.66) | 0.98 (0.47-2.05) | 0.954 |
Other upper respiratory disease | 8 (7.62) | 0.65 (0.32-1.34) | 1.21 (0.59-2.49) | 0.608 |
Spondylosis; intervertebral disc disorders; other back problems | 8 (7.62) | 1.21 (0.59-2.49) | 0.72 (0.35-1.49) | 0.376 |
Asthma | 7 (6.67) | 0.9 (0.42-1.95) | 2.66 (1.23-5.77) | 0.013* |
Chronic ulcer of skin | 7 (6.67) | 2.54 (1.18-5.48) | 0.93 (0.43-2.04) | 0.857 |
Heart valve disorders | 6 (5.71) | 5.95 (2.61-13.56) | 2.99 (1.31-6.85) | 0.010* |
Diverticulosis and diverticulitis | 6 (5.71) | 3.48 (1.52-7.92) | 1.83 (0.79-4.18) | 0.154 |
Headache; including migraine | 5 (4.76) | 0.38 (0.16-0.93) | 0.65 (0.26-1.60) | 0.350 |
Miscellaneous mental health disorders | 5 (4.76) | 0.76 (0.31-1.87) | 0.81 (0.33-2.00) | 0.655 |
Cancer of bronchus; lung | 4 (3.81) | 5.18 (1.91-14.07) | 2.38 (0.87-6.51) | 0.090 |
Cancer of prostate | 4 (3.81) | 2.07 (0.76-5.63) | 0.81 (0.29-2.24) | 0.691 |
Epilepsy; convulsions | 4 (3.81) | 3.06 (1.13-8.31) | 3.43 (1.26-9.31) | 0.016* |
Retinal detachments; defects; vascular occlusion; and retinopathy | 4 (3.81) | 2.88 (1.06-7.82) | 1.54 (0.56-4.19) | 0.398 |
Acute cerebrovascular disease | 4 (3.81) | 1.26 (0.46-3.42) | 0.48 (0.18-1.34) | 0.163 |
Peripheral and visceral atherosclerosis | 4 (3.81) | 2.36 (0.87-6.42) | 1.09 (0.40-2.99) | 0.857 |
Aortic; peripheral; and visceral artery aneurysms | 4 (3.81) | 7.58 (2.79-20.6) | 3.39 (1.24-9.28) | 0.017* |
Other diseases of veins and lymphatics | 4 (3.81) | 38.23 (14.03-104.21) | 23.12 (8.45-63.25) | 0.000* |
Esophageal disorders | 4 (3.81) | 1.18 (0.43-3.21) | 0.99 (0.36-2.69) | 0.985 |
Other inflammatory condition of skin | 4 (3.81) | 1.00 (0.37-2.72) | 0.88 (0.33-2.41) | 0.813 |
Residual codes; unclassified | 4 (3.81) | 1.12 (0.41-3.05) | 0.89 (0.33-2.42) | 0.823 |
Other endocrine disorders | 3 (2.86) | 12.37 (3.92-39.05) | 7.77 (2.46-24.58) | 0.000* |
Other nervous system disorders | 3 (2.86) | 1.06 (0.34-3.34) | 0.79 (0.25-2.49) | 0.689 |
Peri-; endo-; and myocarditis; cardiomyopathy (except that caused by tuberculosis or sexually transmitted disease) | 3 (2.86) | 3.82 (1.21-12.05) | 2.25 (0.71-7.11) | 0.167 |
Transient cerebral ischemia | 3 (2.86) | 1.45 (0.46-4.56) | 0.55 (0.17-1.74) | 0.307 |
Other liver diseases | 3 (2.86) | 1.23 (0.39-3.89) | 0.88 (0.28-2.80) | 0.840 |
Alcohol-related disorders | 3 (2.86) | 1.07 (0.34-3.39) | 0.95 (0.30-3.01) | 0.937 |