Table 3 Logistic regression models were used to calculate odds ratios (OR) of prevalence for each comorbidity (dependent variable) according to the presence or absence of breast cancer in men (independent variable).

From: Unveiling the comorbidity burden of male breast cancer

Comorbidity

Prevalence

Crude OR

Adjusted OR1

p-value2

(n, %)

(95% CI)

(95% CI)

Disorders of lipid metabolism

58 (55.24)

2.46 (1.67-3.62)

1.38 (0.94-2.04)

0.104

Hypertension

52 (49.52)

1.91 (1.30-2.79)

0.62 (0.41-0.93)

0.019*

Other nutritional; endocrine; and metabolic disorders

34 (32.38)

1.87 (1.24-2.82)

1.15 (0.76-1.73)

0.509

Diabetes Mellitus

30 (28.57)

2.6 (1.70-3.98)

1.26 (0.81-1.93)

0.303

Anxiety disorders

22 (20.95)

1.66 (1.04-2.66)

1.65 (1.03-2.65)

0.036*

Cardiac dysrhythmias

21 (20.00)

3.25 (2.02-5.25)

1.43 (0.88-2.34)

0.150

Genitourinary symptoms and ill-defined conditions

21 (20.00)

3.98 (2.47-6.42)

1.48 (0.89-2.44)

0.129

Osteoarthritis

21 (20.00)

2.36 (1.46-3.80)

1.01 (0.62-1.64)

0.982

Cataract

17 (16.19)

2.15 (1.28-3.61)

0.80 (0.47-1.37)

0.415

Obesity

17 (16.19)

1.75 (1.04-2.94)

1.48 (0.88-2.49)

0.141

Hyperplasia of prostate

16 (15.24)

1.78 (1.05-3.03)

0.65 (0.37-1.12)

0.119

Other ear and sense organ disorders

14 (13.33)

1.62 (0.92-2.85)

1.14 (0.65-2.00)

0.652

Coagulation and hemorrhagic disorders

13 (12.38)

2.83 (1.58-5.05)

1.25 (0.69-2.25)

0.462

Thyroid disorders

12 (11.43)

2.42 (1.33-4.41)

1.81 (0.99-3.31)

0.053

Acute myocardial infarction

12 (11.43)

2.5 (1.37-4.56)

1.13 (0.61-2.08)

0.695

Depression and mood disorders

12 (11.43)

1.21 (0.66-2.20)

0.86 (0.47-1.57)

0.621

Glaucoma

10 (9.52)

2.04 (1.06-3.92)

0.95 (0.49-1.83)

0.876

Chronic obstructive pulmonary disease and bronchiectasis

10 (9.52)

1.76 (0.92-3.38)

0.73 (0.37-1.41)

0.342

Osteoporosis

10 (9.52)

9.08 (4.73-17.42)

4.26 (2.2-8.24)

0.000*

Delirium, dementia, and amnestic and other cognitive disorders

10 (9.52)

1.82 (0.95-3.50)

0.82 (0.42-1.58)

0.550

Chronic kidney disease

9 (8.57)

2.11 (1.07-4.18)

0.82 (0.41-1.65)

0.582

Gout and other crystal arthropathies

8 (7.62)

1.63 (0.79-3.34)

0.85 (0.41-1.75)

0.656

Blindness and vision defects

8 (7.62)

0.92 (0.45-1.90)

1.10 (0.53-2.26)

0.797

Congestive heart failure; nonhypertensive

8 (7.62)

2.75 (1.34-5.66)

0.98 (0.47-2.05)

0.954

Other upper respiratory disease

8 (7.62)

0.65 (0.32-1.34)

1.21 (0.59-2.49)

0.608

Spondylosis; intervertebral disc disorders; other back problems

8 (7.62)

1.21 (0.59-2.49)

0.72 (0.35-1.49)

0.376

Asthma

7 (6.67)

0.9 (0.42-1.95)

2.66 (1.23-5.77)

0.013*

Chronic ulcer of skin

7 (6.67)

2.54 (1.18-5.48)

0.93 (0.43-2.04)

0.857

Heart valve disorders

6 (5.71)

5.95 (2.61-13.56)

2.99 (1.31-6.85)

0.010*

Diverticulosis and diverticulitis

6 (5.71)

3.48 (1.52-7.92)

1.83 (0.79-4.18)

0.154

Headache; including migraine

5 (4.76)

0.38 (0.16-0.93)

0.65 (0.26-1.60)

0.350

Miscellaneous mental health disorders

5 (4.76)

0.76 (0.31-1.87)

0.81 (0.33-2.00)

0.655

Cancer of bronchus; lung

4 (3.81)

5.18 (1.91-14.07)

2.38 (0.87-6.51)

0.090

Cancer of prostate

4 (3.81)

2.07 (0.76-5.63)

0.81 (0.29-2.24)

0.691

Epilepsy; convulsions

4 (3.81)

3.06 (1.13-8.31)

3.43 (1.26-9.31)

0.016*

Retinal detachments; defects; vascular occlusion; and retinopathy

4 (3.81)

2.88 (1.06-7.82)

1.54 (0.56-4.19)

0.398

Acute cerebrovascular disease

4 (3.81)

1.26 (0.46-3.42)

0.48 (0.18-1.34)

0.163

Peripheral and visceral atherosclerosis

4 (3.81)

2.36 (0.87-6.42)

1.09 (0.40-2.99)

0.857

Aortic; peripheral; and visceral artery aneurysms

4 (3.81)

7.58 (2.79-20.6)

3.39 (1.24-9.28)

0.017*

Other diseases of veins and lymphatics

4 (3.81)

38.23 (14.03-104.21)

23.12 (8.45-63.25)

0.000*

Esophageal disorders

4 (3.81)

1.18 (0.43-3.21)

0.99 (0.36-2.69)

0.985

Other inflammatory condition of skin

4 (3.81)

1.00 (0.37-2.72)

0.88 (0.33-2.41)

0.813

Residual codes; unclassified

4 (3.81)

1.12 (0.41-3.05)

0.89 (0.33-2.42)

0.823

Other endocrine disorders

3 (2.86)

12.37 (3.92-39.05)

7.77 (2.46-24.58)

0.000*

Other nervous system disorders

3 (2.86)

1.06 (0.34-3.34)

0.79 (0.25-2.49)

0.689

Peri-; endo-; and myocarditis; cardiomyopathy (except that caused by tuberculosis or sexually transmitted disease)

3 (2.86)

3.82 (1.21-12.05)

2.25 (0.71-7.11)

0.167

Transient cerebral ischemia

3 (2.86)

1.45 (0.46-4.56)

0.55 (0.17-1.74)

0.307

Other liver diseases

3 (2.86)

1.23 (0.39-3.89)

0.88 (0.28-2.80)

0.840

Alcohol-related disorders

3 (2.86)

1.07 (0.34-3.39)

0.95 (0.30-3.01)

0.937

  1. 1 odds ratios adjusted by age; 2 p-values for the adjusted OR; * p<0.05.