Table 4 Logistic regression models were used to calculate odds ratios (OR) of prevalence for each comorbidity (dependent variable) according to the presence or absence of breast cancer in women (independent variable).
From: Unveiling the comorbidity burden of male breast cancer
Comorbidity | Prevalence | Crude OR | Adjusted OR1 | p-value2 |
|---|---|---|---|---|
(n, %) | (95% CI) | (95% CI) | ||
Hypertension | 5811 (49,85) | 2.08 (2.00-2.15) | 0.88 (0.85-0.92) | 0.000* |
Disorders of lipid metabolism | 5062 (43,42) | 1.76 (1.69-1.82) | 1.07 (1.03-1.11) | 0.001* |
Depression and mood disorders | 3242 (27,81) | 1.55 (1.49-1.62) | 1.16 (1.11-1.21) | 0.000* |
Anxiety disorders | 3136 (26,9) | 1.10 (1.06-1.15) | 1.08 (1.04-1.13) | 0.000* |
Other nutritional; endocrine; and metabolic disorders | 3088 (26,49) | 1.49 (1.43-1.56) | 1.06 (1.02-1.11) | 0.006* |
Osteoarthritis | 3076 (26,39) | 1.79 (1.72-1.87) | 0.98 (0.94-1.02) | 0.344 |
Osteoporosis | 2931 (25,14) | 2.48 (2.37-2.58) | 1.45 (1.39-1.52) | 0.000* |
Thyroid disorders | 2344 (20,11) | 1.15 (1.1-1.21) | 0.98 (0.94-1.03) | 0.375 |
Genitourinary symptoms and ill-defined conditions | 2089 (17,92) | 1.54 (1.47-1.62) | 0.77 (0.73-0.81) | 0.000* |
Cataract | 1911 (16,39) | 1.87 (1.78-1.96) | 0.99 (0.94-1.04) | 0.676 |
Diabetes Mellitus | 1809 (15,52) | 1.77 (1.68-1.86) | 1.04 (0.98-1.09) | 0.168 |
Headache; including migraine | 1686 (14,46) | 0.67 (0.63-0.7) | 0.94 (0.89-0.99) | 0.021* |
Obesity | 1568 (13,45) | 1.16 (1.09-1.22) | 1.00 (0.95-1.06) | 0.940 |
Spondylosis; intervertebral disc disorders; other back problems | 1470 (12,61) | 1.58 (1.49-1.67) | 1.08 (1.02-1.14) | 0.007* |
Delirium, dementia, and amnestic and other cognitive disorders | 1275 (10,94) | 1.40 (1.32-1.49) | 0.72 (0.68-0.77) | 0.000* |
Other ear and sense organ disorders | 1185 (10,16) | 1.34 (1.26-1.42) | 1.01 (0.95-1.07) | 0.866 |
Menopausal disorders | 1172 (10,05) | 1.14 (1.08-1.22) | 0.94 (0.89-1.00) | 0.069 |
Cardiac dysrhythmias | 1137 (9,75) | 1.72 (1.62-1.83) | 0.98 (0.92-1.04) | 0.452 |
Blindness and vision defects | 1088 (9,33) | 0.97 (0.91-1.03) | 1.14 (1.07-1.21) | 0.000* |
Other upper respiratory disease | 995 (8,54) | 0.67 (0.63-0.72) | 1.01 (0.95-1.08) | 0.718 |
Menstrual disorders | 980 (8,41) | 0.38 (0.35-0.40) | 0.72 (0.67-0.77) | 0.000* |
Glaucoma | 965 (8,28) | 1.64 (1.53-1.75) | 0.98 (0.91-1.05) | 0.544 |
Chronic kidney disease | 763 (6,55) | 1.58 (1.47-1.71) | 0.83 (0.77-0.90) | 0.000* |
Asthma | 760 (6,52) | 0.75 (0.70-0.81) | 0.98 (0.91-1.05) | 0.536 |
Acquired foot deformities | 746 (6,4) | 1.43 (1.32-1.54) | 1.10 (1.02-1.19) | 0.010* |
Other nervous system disorders | 724 (6,21) | 1.12 (1.03-1.20) | 1.00 (0.92-1.08) | 0.948 |
Coagulation and hemorrhagic disorders | 712 (6,11) | 1.60 (1.48-1.73) | 0.94 (0.87-1.02) | 0.141 |
Congestive heart failure; nonhypertensive | 648 (5,56) | 1.73 (1.59-1.87) | 0.85 (0.78-0.92) | 0.000* |
Other diseases of veins and lymphatics | 590 (5,06) | 15.05 (13.71-16.52) | 10.74 (9.76-11.81) | 0.000* |
Chronic ulcer of skin | 566 (4,86) | 1.44 (1.32-1.57) | 0.68 (0.62-0.74) | 0.000* |
Esophageal disorders | 495 (4,25) | 1.22 (1.11-1.33) | 1.05 (0.95-1.15) | 0.341 |
Miscellaneous mental health disorders | 469 (4,02) | 0.64 (0.58-0.70) | 0.82 (0.75-0.90) | 0.000* |
Acute cerebrovascular disease | 452 (3,88) | 1.53 (1.39-1.68) | 0.79 (0.71-0.87) | 0.000* |
Diverticulosis and diverticulitis | 426 (3,65) | 1.82 (1.65-2.00) | 1.12 (1.02-1.24) | 0.024* |
Other inflammatory condition of skin | 420 (3,6) | 1.08 (0.98-1.19) | 1.11 (1.01-1.23) | 0.031* |
Prolapse of female genital organs | 413 (3,54) | 1.50 (1.36-1.66) | 1.02 (0.92-1.12) | 0.758 |
Acute myocardial infarction | 409 (3,51) | 1.66 (1.50-1.84) | 0.91 (0.82-1.01) | 0.078 |
Transient cerebral ischemia | 365 (3,13) | 1.53 (1.37-1.70) | 0.79 (0.71-0.88) | 0.000* |
Other gastrointestinal disorders | 361 (3,10) | 1.21 (1.09-1.35) | 1.14 (1.02-1.26) | 0.019* |
Chronic obstructive pulmonary disease and bronchiectasis | 352 (3,02) | 1.49 (1.34-1.66) | 0.92 (0.82-1.02) | 0.113 |
Adjustment disorders | 350 (3,00) | 1.32 (1.18-1.47) | 1.04 (0.94-1.16) | 0.440 |
Other eye disorders | 336 (2,88) | 1.37 (1.23-1.53) | 1.18 (1.06-1.32) | 0.003* |
Nonmalignant breast conditions | 308 (2,64) | 1.00 (0.89-1.12) | 1.21 (1.08-1.36) | 0.001* |
Allergic reactions | 298 (2,55) | 0.36 (0.32-0.4) | 1.79 (1.59-2.01) | 0.000* |
Retinal detachments; defects; vascular occlusion; and retinopathy | 284 (2,44) | 1.64 (1.45-1.85) | 1.02 (0.9-1.15) | 0.768 |
Other liver diseases | 260 (2,23) | 1.66 (1.46-1.88) | 1.28 (1.13-1.45) | 0.000* |
Heart valve disorders | 247 (2,12) | 1.90 (1.67-2.16) | 1.18 (1.04-1.34) | 0.013* |
Other non-traumatic joint disorders | 200 (1,72) | 1.08 (0.94-1.25) | 0.99 (0.86-1.14) | 0.907 |
Other acquired deformities | 185 (1,59) | 0.53 (0.46-0.62) | 0.97 (0.84-1.13) | 0.716 |
Conduction disorders | 181 (1,55) | 1.64 (1.41-1.90) | 1.04 (0.89-1.20) | 0.648 |
Rheumatoid arthritis and related disease | 172 (1,48) | 1.24 (1.07-1.45) | 0.92 (0.79-1.07) | 0.285 |
Diseases of white blood cells | 159 (1,36) | 0.85 (0.73-1.00) | 0.93 (0.79-1.09) | 0.364 |
Endometriosis | 155 (1,33) | 1.71 (1.46-2.01) | 2.12 (1.80-2.49) | 0.000* |
Epilepsy; convulsions | 143 (1,23) | 1.13 (0.96-1.34) | 1.16 (0.98-1.38) | 0.078 |
Joint disorders and dislocations; trauma-related | 141 (1,21) | 0.98 (0.83-1.16) | 1.20 (1.01-1.42) | 0.035* |
Residual codes; unclassified | 141 (1,21) | 1.22 (1.03-1.44) | 1.07 (0.90-1.26) | 0.456 |
Parkinson`s disease | 136 (1,17) | 1.49 (1.25-1.76) | 0.78 (0.65-0.93) | 0.004* |
Other hereditary and degenerative nervous system conditions | 136 (1,17) | 1.42 (1.20-1.68) | 1.02 (0.86-1.22) | 0.794 |
Other circulatory disease | 127 (1,09) | 0.92 (0.77-1.10) | 0.75 (0.63-0.90) | 0.001* |
Gout and other crystal arthropathies | 123 (1,06) | 1.51 (1.26-1.81) | 0.89 (0.74-1.07) | 0.214 |
