Table 1 Clinical and laboratory characteristics of the analyzed patients.

From: Association between the lactate-albumin ratio and microcirculation changes in Pediatric Septic patients

Characteristic

Total n = 178

Elevated LAR n = 50

Normal LAR n = 128

P value1

Age, months (IQR)

23.1 (6.1-120.1)

52.5 (7.2-144.7)

12.0 (6.1-102.8)

0.1

Weight, kg (IQR)

10.8 (6.4–29.9)

17.0 (6.8–31.0)

10 (6.4–28.4)

0.35

Female sex (%)

84 (47.2)

25 (50)

59 (46.1)

0.76

Days in PICU (IQR)

12.0 (7.0–22.0)

14.0 (6.5–22.5)

12 (7.0–19.0)

0.91

Focus of infection (%)

   

0.34

 Respiratory

61 (35.3)

20 (40.8)

41 (33.1)

 

 Gastrointestinal tract

42 (24.3)

14 (28.6)

28 (22.6)

 

 Central nervous system

9 (5.2)

1.0 (2.0)

8.0 (6.5)

 

 Other

61 (35.3)

14 (28.6)

47.0 (37.9)

 

Local sepsis (%)

61 (34.2)

9 (18)

52 (40.6)

0.53

Remote sepsis (%)

117 (65.7)

41 (82)

76 (59.4)

0.46

PIM-2 (IQR)

15 (6.5–26)

18.7 (6.7–26.5)

14 (6.3–25.6)

0.57

PELOD-2 score (IQR)

6.0 (3.0–9.0)

6.0 (3–8.0)

7.0 (3.0–9.0)

0.29

Phoenix Sepsis Score

4.0 (3.0–5.0)

4.0 (4.0–5.0)

4.0 (2.5-4.0)

0.01

Lactate, mmol/L

2.45 (1.9–3.7)

2.8 (2.4–3.2)

2.2 (1.9–2.3)

0.08

Albumin, g/dL

3.0 (2.2–3.6)

2.8 (2.5-3.0)

3.2 (2.9–3.4)

0.12

Glucose mg/dL (IQR)

114.0 (94.6-139.5)

121.0 (99.4–149.0)

108.6 (91.6-132.5)

0.04

Ferritin mg/dL (IQR)

424 (190-1586.4)

583.2 (298-2130.5)

373.5 (160-1265.8)

0.02

C-reactive protein, mg/dL (IQR)

4.7 (1.6–11.4)

5.3 (1.6–12.6)

4.4 (1.6–9.1)

0.61

D-dimer, mg/L (IQR)

3.6 (1.6–8.3)

4.3 (2.1–8.3)

3.5 (1.2–8.4)

0.48

Procalcitonin, g/dL (IQR)

1.4 (0.4-5.0)

2.1 (0.9–13.3)

1.1 (0.3–4.3)

< 0.01

Creatinine, mg/dL (IQR)

0.4 (0.3–0.6)

0.5 (0.3–0.8)

0.4 (0.3–0.6)

0.08

Vasoactive score (IQR)

10 (5.0-28.4)

19 (6.2–31.9)

7.5 (4.0-24.1)

0.01

Mechanical ventilation (%)

152 (87.9)

44 (89.8)

108 (87.1)

0.81

Mortality (%)

21.0 (12.1)

11 (22.9)

10 (8.0)

0.01

  1. An LAR (lactate-albumin ratio) greater than 0.5 is considered elevated, and equal to or less than 0.49 is considered normal1. Statistically significant p values are in bold (p < 0.05). P-values by Student’s t test, Chi-square test, or Mann–Whitney U test, as applicable. Those not labeled were analyzed using the Chi-square test. PIM-2: Pediatric Index of Mortality-2; PELOD-2: Pediatric Logistic Organ Dysfunction-2. PICU: pediatric intensive care unit. IQR: interquartile range.
Back to article page