Table 4 Minimum inhibitory concentration (MIC, µg /mL) data of fluconazole (FLZ), itraconazole (ITZ), ketoconazole (KTZ), posaconazole (POS), voriconazole (VOR), amphotericin (AmB) and anidulafungin (ANI) of isolated yeast species from snakes coming from Group I (Marrakech, Morocco) and Group II (Cocullo, Abruzzo, Italy).

Group I (Marrakech, Morocco)

Candida parapsilosis (n = 2)

Range

0.5

0.06

0.03

0.25

0.015

0.5

1

MICm (SD)

0.5 (0)^a

0.06 (0)^b

0.03 (0)^c

0.25 (0)^d

0.015 (0)^e

0.5 (0)^f

1 (0)^g

Candida tropicalis (n = 11)

Range

0.5–64

0.06–16

0.06–4

0.125–16

0.03–16

1

0.25–0.5

MICm (SD)

47.3 (25.4)^ahov3*§

11.67 (7.07)^{bipz4^°}

2.23 (1.51)^cjqw5àù

11.7 (7.01)^dkrx6&$

8.77 (6.27)^elsy7§+

1 (0.01)^fmt18èì

0.37 (0.1)^gnu29ù#

Clavispora lusitaniae (n = 1)

Range

1

0.125

0.06

4

8

1

1

MICm (SD)

1 (0)

0.125 (0)

0.06 (0)

4 (0)

8 (0)

1 (0)

1 (0)

Diutina catelunata (n = 3)

Range

2

0.03

0.06

0.06

0.03

0.5

0.25

MICm (SD)

2 (0)^h

0.03 (0)ⁱ

0.06 (0)^j

0.06 (0)^k

0.03 (0)^l

0.5 (0)^m

0.25 (0)ⁿ

Exophiala dermatitidis (n = 2)

Range

4

0.25

0.25

0.5

0.062

0.5

1

MICm (SD)

4 (0)^o

0.25 (0)^p

0.25 (0)^q

0.5 (0)^r

0.062 (0)^s

0.5 (0)^t

1 (0)^u

Meyerozyma caribbica (n = 2)

Range

0.5

0.125

0.06

0.25

8

1

1

MICm (SD)

0.5 (0)^v

0.125 (0)^z

0.06 (0)^w

0.25 (0)^x

8 (0)^y

1 (0)¹

1 (0)²

Rhodotorula mucilaginosa (n = 2)

Range

0.5

0.03

0.06

0.25

0.015

1

0.5

MICm (SD)

0.5 (0)³

0.03 (0)⁴

0.06 (0)⁵

0.25 (0)⁶

0.015 (0)⁷

1 (0)⁸

0.5 (0)⁹

Trichosporon asahii (n = 16)

Range

0.06–0.25

0.25–2

0.03–0.5

0.25–0.5

0.015–0.032

0.5–2

0.5–16

MICm (SD)

0.18 (0.07)^*

1.16 (0.56)^{^}

0.29 (0.22)^à

0.38 (0.13)^&

0.0278 (0.005)^ç

1.12 (0.54) ^è

5.6 (6.4)^ù

Wickerhamiella pararugosa (n = 1)

Range

8

0.25

0.5

0.5

0.5

1

0.5

MICm (SD)

8 (0)^§

0.25 (0)^°

0.5 (0) ^ù

0.5 (0)^$

0.5 (0)⁺

1 (0) ^ì

0.5 (0)^#

Group II (Cocullo, Abruzzo, Italy)

Cryptococcus neoformans (n = 4)

Range

0.5

0.5

0.125–0.25

0.5–1

0.062–0.125

1

16

MICm (SD)

0.5 (0)

0.5 (0)

0.16 (0.05)

0.83 (0.23)

0.08 (0.03)

1 (0)

16 (0)

Debaryomyces spp. (n = 12)

Range

0.032–0.25

0.125–0.5

0.032

0.062–0.25

0.016

1

0.062–0.25

MICm (SD)

0.13 (0.08)

0.29 (0.15)

0.032 (6.94 × 10^–18)

0.18 (0.09)

0.016 (3.47 × 10^–18)

1.33 (0.47)

0.14 (0.07)

Metahyphopichia silvanorum (n = 8)

Range

0.25

0.5–2

0.032–0.125

0.25–0.5

0.03

0.5–1

0.5–16

MICm (SD)

0.25 (0)

1 (0.70)

0.07 (0.04)

0.41 (0.11)

0.032 ( (6.94 × 10^–18)

0.83 (0.23)

5.66 (7.30)

Meyerozyma guilliermondii (n = 4)

Range

2

2

0.5

1

0.25

2

4

MICm (SD)

2 (0)

2 (0)

0.5 (0)

1 (0)

0.25 (0)

2 (0)

4 (0)

Rhodotorula mucilaginosa (n = 4)

Range

> 64

2

0.25

1–2

1

0.5–1

8–>16

MICm (SD)

> 64 (0)

2 (0)

0.25 (0)

1.5 (0.5)

1 (0)

0.75 (0.25)

12 (4)