Table 4 Estimated mean volumes and the corresponding p-values from the analyses of covariance (ANCOVAs) of early-onset schizophrenia/adult-onset schizophrenia (EOS/AOS) status on left and right subcortical volumes among adult patients with schizophrenia spectrum disorders currently on antipsychotics.

From: Caudate nucleus volume in medicated and unmedicated patients with early- and adult-onset schizophrenia

Volumes in mm3

Left hemisphere

Right hemisphere

EOS

AOS

P-value

EOS

AOS

P-value

N

74

220

 

74

220

 

Accumbens

589

585

0.762

610

597

0.290

Amygdala

1584

1604

0.447

1780

1755

0.314

Caudate

3948

3756

< 0.001*

4001

3835

0.003*

Hippocampus

4091

4132

0.352

4181

4201

0.661

Pallidum

2151

2114

0.154

2146

2100

0.082

Putamen

5459

5378

0.218

5494

5401

0.141

Thalamus

7885

7854

0.704

7215

7229

0.852

  1. Nominally significant associations (p < 0.05) are shown in bold.
  2. *Survives false discovery rate (FDR) correction for multiple testing.
  3. *p < 0.05.
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