Table 6 GO and KEGG pathway enrichment analysis of the top 20 positively correlated genes with 12-gene signature in TCGA-LUAD patients.
Category | ID | Term | adj_pval |
|---|---|---|---|
BP | GO:0030198 | Extracellular matrix organization | 1.52542E−09 |
BP | GO:0043062 | Extracellular structure organization | 1.52542E−09 |
BP | GO:0043588 | Skin development | 0.009218619 |
BP | GO:0048565 | Digestive tract development | 0.009218619 |
BP | GO:0022600 | Digestive system process | 0.009218619 |
BP | GO:0007586 | Digestion | 0.009218619 |
BP | GO:0030277 | Maintenance of gastrointestinal epithelium | 0.009218619 |
BP | GO:0055123 | Digestive system development | 0.010558369 |
BP | GO:0070268 | Cornification | 0.012095677 |
BP | GO:0031589 | Cell-substrate adhesion | 0.012095677 |
CC | GO:0062023 | Collagen-containing extracellular matrix | 6.76853E−07 |
CC | GO:0005604 | Basement membrane | 1.77046E−05 |
CC | GO:0030175 | Filopodium | 0.002895847 |
CC | GO:0044420 | Extracellular matrix component | 0.00440781 |
CC | GO:0098858 | Actin-based cell projection | 0.00440781 |
CC | GO:0005581 | Collagen trimer | 0.004661637 |
CC | GO:0008305 | Integrin complex | 0.005193845 |
MF | GO:0005201 | Extracellular matrix structural constituent | 1.05889E−05 |
MF | GO:0050839 | Cell adhesion molecule binding | 0.000515535 |
MF | GO:0015250 | Water channel activity | 0.013488077 |
MF | GO:0005372 | Water transmembrane transporter activity | 0.013488077 |
KEGG | hsa04512 | ECM-receptor interaction | 0.00051659 |
KEGG | hsa04151 | PI3K-Akt signaling pathway | 0.005110996 |
KEGG | hsa04510 | Focal adhesion | 0.012081601 |
