Fig. 7 | Scientific Reports

Fig. 7

From: Identification of immune patterns in idiopathic pulmonary fibrosis patients driven by PLA2G7-positive macrophages using an integrated machine learning survival framework

Fig. 7

Celecoxib exerts anti-inflammatory effects by targeting PLA2G7. (A) Schematic representation of the binding mode of molecules with PLA2G7. (B) Affinity between small molecules and PLA2G7. (C) Surface plasmon resonance analysis of celecoxib and PLA2G7. Celecoxib, as the ligand, was dissolved and injected at concentrations of 0 µM, 0.19 µM (purple), 0.39 µM (black), 0.78 µM (blue), 1.56 µM (orange), 3.13 µM (green), and 6.25 µM (red).

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