Fig. 2

Anti-MICA/MICB antibody 6D4 blocks activation of T cells by coculture. (a) IFNG mRNA expression of NKG2D^High (left) and NKG2D^Low (right) CD8 T cells cocultured with PANC-1 cells with or without 6D4 antibody at 100 nM. Data are mean with SEM from three independent experiments. (b) Apoptotic PANC-1 cells after coculture with NKG2D^High (left) or NKG2D^Low (right) CD8 T cells with or without 6D4 antibody at 100 nM. Data are mean with SEM from three independent experiments.