Table 4 Simple and multiple logistic regression analyses of prognostic factors associated with ICU survival.

From: Presence of cholestasis and its impact on survival in SARS-CoV-2 associated acute respiratory distress syndrome

Parameter

Simple

Multiple

OR (95%CI)

P

OR (95%CI)

P

Cholestasis

0.515 (0.294–0.891)

0.019

  

ECMO

0.650 (0.370–1.127)

0.128

  

ICU LOS

1.008 (0.999–1.018)

0.096

1.061 (1.037–1.089)

< 0.001

Cumulative Days Norepinephrine

0.983 (0.967-1.000)

0.048

0.932 (0.886–0.976)

0.004

Cumulative Days of ketamine

0.974 (0.949–0.998)

0.039

  

Cumulative Days of NMB

0.949 (0.894–1.005)

0.073

1.073 (0.984–1.17)

0.108

Cumulative Days of PN

0.962 (0.930–0.993)

0.018

  

Cumulative Days of IMV

1.004 (0.994–1.014)

0.464

  

Peak AST*

0.521 (0.375–0.698)

< 0.001

0.619 (0.396–0.937)

0.028

Peak CRP

0.971 (0.945–0.997)

0.029

  

Peak IL-6*

0.625 (0.512–0.753)

0.028

0.659 (0.474–0.901)

0.010

Peak PCT*

0.621 (0.505–0.753)

< 0.001

0.772 (0.572–1.032)

0.084

P/F ratio nadir

1.046 (1.026–1.070)

< 0.001

1.048 (1.024–1.075)

< 0.001

Prone position

0.629 (0.307–1.235)

0.189

  

SOFA Score

0.766 (0.673–0.863)

< 0.001

  
  1. OR, odds ratio; CI, confidence interval; ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; LOS, length of stay; NMB, neuromuscular blockade; PN, parenteral nutrition; IMV, invasive mechanical ventilation; CRP, C-reactive protein; IL-6, interleukin-6; PCT, procalcitonin; P/F ratio, PaO2/FiO2 ratio; SOFA, Sequential Organ Failure Assessment Score.
  2. *logarithmized.
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