Table 1 Basic demographics and clinical characteristics of enrolled subjects.
Variables | Healthy (n = 117) | CD (n = 223) | UC (n = 300) | P value | Statistical test |
|---|---|---|---|---|---|
Demographics | |||||
Age at index date (years) | 42.1 ± 15.9 | 33.9 ± 11.7 | 47.2 ± 15.0 | < 0.01 | Kruskal-Wallis |
Gender, Female (%) | 75 (64.1%) | 55 (24.7%) | 132 (44.0%) | < 0.01 | Chi-square |
BMI (kg/m2) | 23.7 ± 3.4 | 22.3 ± 3.8 | 23.2 ± 2.8 | < 0.01 | Kruskal-Wallis |
Height (cm) | 164.9 ± 9.6 | 170.1 ± 8.0 | 165.5 ± 8.3 | < 0.01 | Kruskal-Wallis |
Weight (kg) | 64.6 ± 12.3 | 65.0 ± 13.9 | 63.7 ± 10.6 | 0.88 | Kruskal-Wallis |
Current smoker | 9 (7.7%) | 25 (11.2%) | 15 (5.0%) | < 0.01 | Chi-square |
Current alcohol consumption | 43 (36.8%) | 80 (35.9%) | 103 (34.3%) | 0.877 | Chi-square |
Bristol Stool Scale score | 4.00 ± 0.99 | 4.29 ± 1.31 | 4.02 ± 1.04 | < 0.01 | Chi-square |
IBD characteristics | |||||
Disease duration (years) | 8.70 ± 5.78 | 8.88 ± 6.65 | |||
Montreal classification | |||||
L1, ileal | 63 (28.1%) | ||||
L2, colonic | 11 (4.91%) | ||||
L3, ileocolonic | 149 (66.9%) | ||||
B1, inflammatory | 128 (57.4%) | ||||
B2, stricturing | 48 (21.4%) | ||||
B3, penetrating | 47 (20.9%) | ||||
P, perianal disease | 110 (49.3%) | ||||
E1, proctitis | 78 (26%) | ||||
E2, left-sided | 104 (34.6%) | ||||
E3, extensive | 121 (40.3%) | ||||
Current treatment | |||||
Biologics, current use | 172 (77.1%) | 79 (26.3%) | |||
Immunomodulator, any | 119 (53.3%) | 119 (39.6%) | |||
Small molecules | N/A | 13 (4.3%) | |||
Steroid | 5 (2.2%) | 1 (0.3%) | |||
Disease activity | |||||
HBI score | 1.93 ± 4.53 | ||||
Partial Mayo score | 1.76 ± 2.04 | ||||
