Table 2 Composition of MN- ME in situ gel formulation.

From: Development of synergistic antifungal in situ gel of miconazole nitrate loaded microemulsion as a novel approach to treat vaginal candidiasis

Formula

ME formula

Mucoadhesive in situ gel formula

Dilution ratio (ME to in situ gel)

MG1

ME10

IS-I

1:1

MG2

ME10

IS-I

1:2

MG3

ME10

IS-I

1:3

MG4

ME10

IS-I

1:4

MG5

ME10

IS-I

1:5

MG6

ME7

IS-I

1:1

MG7

ME7

IS-I

1:2

MG8

ME7

IS-I

1:3

MG9

ME7

IS-I

1:4

MG10

ME7

IS-I

1:5

MG11

ME10

IS-II

1:1

MG12

ME10

IS-II

1:2

MG13

ME10

IS-II

1:3

MG14

ME10

IS-II

1:4

MG15

ME10

IS-II

1:5

MG16

ME7

IS-II

1:1

MG17

ME7

IS-II

1:2

MG18

ME7

IS-II

1:3

MG19

ME7

IS-II

1:4

MG20

ME7

IS-II

1:5

  1. IS-I: Mucoadhesive in situ gel (18% PLX 407, 2% PLX 188 and 0.6% HPMC K4M).
  2. IS-II: Mucoadhesive in situ gel (18% PLX 407, 2% PLX 188 and 0.6%GG).